Infertility with an incidence of about 10- 1 5% is one of the community burdens that even threatens the continuity of the family life. Intrauterine insemination (IUI) is frequently used in the treatment of infertile couples with various causes of infertility. The difference pregnancy rates following a DOUBLE IVI versus a single IVI has been reported. In this study we compared the effectiveness of DOUBLE IVI before and after ovulation with a single IVI super ovulated cycles with clomiphene citrate. This was a prospective randomized controlled trial study. Our study was carried on 200 women with mild male factor without male factor infertility, and other female factor as an IVI candidate. They were stimulated with clomiphene 100 mg for 5 days plus HCG 10000 IV. On the day of HCG administration, patients were randomly divided into one of two groups; in group I, IVI was performed 36 hours after HCG injection and in group II, DOUBLE IVI was performed 18 and 42 hours after the HCG injection. Clinical pregnancy rates in both groups were compared per cycle. The demographic data for two groups were similar. Pregnancy rate of the first group was 14% versus 13% for the second group, so there was no statistical significance difference between two groups (DOUBLE and single IVI) for the pregnancy rates in super ovulation cycles with clomiphene citrate. (P=0.834) The result of this study did not show benefit for DOUBLE IVI over single IVI in clomiphene citrate/ HCG cycles. Regarding our Findings for future research in IVI candidate couple, using DOUBLE IVI and comparing with single IVI especially with HMG/HCG super ovulation protocol and also infertile couple with male factor is suggested.

Background and Objectives: Brucellae are gram-negative intracellular pathogens which cause zoonotic disease in humans. Clinical manifestations of brucellosis in human are variable and often are non-specific, and the diagnosis requires fast and accurate confirmation. Since the use of serum instead of whole-blood samples offers several advantages for nucleic acid amplification methods, in this study we developed an improved PCR assay for the rapid and specific laboratory diagnosis of human brucellosis directly from serum specimens.Material and Methods: DNA was extracted from 100 µL of serum from 30 patients with acute serologic brucellosis. The PCR reaction was carried out with Specific primers. Second PCR reaction for reamplification of the first reaction products was designed.Results: a 223 bp conserved region on the sequence encoding the 31-KDa immunogenic outer membrane protein which is specific to the genus Brucella (BCSP31) and present in all its biovars was amplified in all serum samples.Conclusion: For confirmation and efficient amplification of the specific target, reamplification of the first PCR products had a sharper banding patterns with high sensitivity and specificity that might be considered as a new useful method for diagnosis of human brucellosis in serum specimens.

BACKGROUND AND OBJECTIVE: In infertility without suffering tubal factor, IUI is the choice therapeutic method. Some studies recommended DOUBLE IUI for every cycle. Since DOUBLE IUI needs more laboratory materials and more expenses, so in this study it was tried to evaluate pregnancy rate in infertile couples after single and DOUBLE IUI.METHODS: This clinical trial study was performed on infertile couples referred to Fatemeh Alzahra or Babol Clinic hospital for IUI cycles. Patients divided into two groups. In the first group, 36 hours after HCG injection, IUI was done as a single protocol and in the other group; IUI was done 24 & 72 hours after HCG injection as DOUBLE protocol. Then data were analyzed by fishers exact test.FINDINGS: Two hundred and fifteen women participated in our study and their mean age was 26.02±5.5 and the mean (±SD) duration of infertility was 3.73 (±2.75) years. In the first group, pregnancy rate was 16.9% and in second group it was 19.6% without any significant difference between two groups. Also, there was no significant difference between groups in pregnancy rate with different etiology of infertility.CONCLUSION: Some studies recommended that DOUBLE IUI is more successful than single IUI But present findings suggest that there is no difference in pregnancy rate between single IUI and DOUBLE IUI.

This study was conducted during summer and winter of 2018- 2019 in the agricultural research field of Shahid Chamran University. Experimental design was split- plot based on RCBD with three replications. The main plot was the type of agricultural system in three levels including conventional (Conv), organic (Org) and sustainable (Sust) (integrated between Conv and Org) and sup- plot was the type of pre- cultivated crop in sequence with wheat including cultivation of mung bean (M- W), corn (C- W), sesame (S- W) and fallow (F- W). Yield quantity (yield and its component) and quality (grain protein), an estimate of photosynthesis matter transfer index of wheat and soil organic carbon (SOC) after one DOUBLE-cropping were measured. The result showed that the highest (545.04 g/m2) and the lowest (409.28 g/m2) seed yields were obtained in Conv and Org respectively. In contract, with the changing type of system from Conv to Org, grain protein was increased significantly (from 8.3 to 9.6 %). In addition, the highest (535.47 g/m2) yield of wheat was obtained from M- W DOUBLE cropping. On the other hands the highest remobilization and current photosynthesis matter were obtained in the organic agricultural system with M- W and conventional with M- W DOUBLE cropping. The situation of SOC showed that the highest (33.18 mg/g) SOC was obtained in the organic agricultural system with C- W DOUBLE cropping. The reason for improving SOC in the organic and sustainable agricultural system was application of organic matter (compost and vermicompost) and crop residue management. Totally, from the crop ecology point of view, sustainable agricultural method with a sequence of M- W was the most desirable system.

Background and Aim: Very little is known about the fracture resistance of endodontically treated teeth restored with different design of esthetic post systems. The aim of this study was to compare the fracture resistance and failure mode of endodontically treated teeth restored with two different types of quartz fiber post.Materials and Methods: In this experimental, in-vitro study, twenty mandibular premolars with similar size were chosen and randomly divided into 2 groups (n=10). After cutting the crowns and endodontic therapy, the teeth were restored with a quartz fiber single taper light-posts in group A and quartz fiber D.T light-post in group B. All posts were cemented with a dual cure cement. Composite resin cores were built up using a pre-formed polyester matrix and every specimen was embedded in an acrylic resin block with a layer of elastic polyether Impergum surrounding the roots as PDL. Compressive load was applied at 135 degree angle to the long axis of the tooth at a crosshead speed of 1mm/min until fracture occurred. T-test was used to determine the significance of the failure load values between the two groups.Results: There was no significant statistical difference in fracture resistance among two groups. The fracture load in groups A and B were 366.7±102.7 (N) and 382.4 ±67.3 (N) respectively. (P<0.6).Conclusion: According to the findings of this study, two different designs of quartz fiber posts did not influence the fracture resistance of endodontically treated teeth.

Background and purpose: Carpal tunnel syndrome is the most prevalent neuropathy caused by trapping and median nerve compression in the wrist. This study aimed at comparing the effects of minimal incision and DOUBLE incision in treatment of patients with carpal tunnel syndrome. Materials and methods: This randomized controlled trial was performed in 50 patients with carpal tunnel syndrome attending Shahid Beheshti and Ayatollah Rouhani hospitals in Babol, Iran, candidates for surgery. The patients were divided into two groups using random number table to have either minimal incision (n=25) or DOUBLE incision (n=25). All patients completed the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) and Visual Analogue Scale (VAS) before and three months after the surgery. Results: The patients included 40 (80%) males and 10 (20%) females. The mean age of the patients was 51. 78± 8. 22 years old. The mean scores for paresthesia, numbness, pain, weakness, nighttime symptoms and functional status (according to BCTQ), and also mean VAS score significantly reduced after the intervention in both groups (P<0. 001). The mean scores for these parameters were not significantly different between the two groups neither before nor after the treatment. Conclusion: The results of treatment with minimal incision and DOUBLE incision were not different, but minimal incision is suggested as a selective therapeutic approach due to smaller cut.

Tuberose (Polianthes tuberosa L.) is one of the most important cut flowers in tropical and subtropical areas. This flower has forth order in cut flower and second order in bulbous plants production in Iran. Plant spacing and nitrogen necessity are the most important factors for tuberose quality and quantity. In this study, field experiment carried out as factorial design in Randomized Complete Block Design (RCBD) format whit 3 replications. Different level of nitrogen (0, 50, 100, 150, 200 and 250 kg/ha) in ammonium nitrate was the first factor. Second factor was different plant spacing (10x10, 15x15, 20x20 and 25x25 cm×cm). Plant space (25×25 cm) has significant effect on flower stalk height, stem diameter, spike length, floret diameter, vase life and also nitrogen, phosphorus and potassium uptake as well. Nitrogen usage as 200 kg/ha N could improved significantly growth indices and yield of tuberose as flower stalk height, stem diameter, spike length and nitrogen uptake.

Let A be a Banach algebra. Let  d, e be linear mappings on A. First we demonstrate a theorem concerning the continuity of DOUBLE derivations; especially that all of (d, e) -DOUBLE derivations are continuous on semi-simple Banach algebras, in certain case. Afterwards we define a new vocabulary called “(d, e) - higher DOUBLE derivation" and present a relation between this subject and derivations and finally give some theorems and corollaries about the automatic continuity of this notion.

Background and Aims: According to the common application of non-metal prefabricated posts in dentistry and lack of enough information about the stress distribution in the root canal walls by these posts, this study was performed to compare the effect of two simple taper and DOUBLE taper posts on the stress distribution on root canal walls by photo elastic method.Materials and Methods: The design of this study was experimental in photoelastic system. The posts, used in this investigation, were DOUBLE taper and simple taper fiber posts with 0.9 mm diameter and 20 mm length and epoxy resin. First two photo elastic models with tooth dimensions were fabricated and the posts were placed inside the model. Then the core of the each post was fabricated on the model. Each models were loaded in polariscope and the formed fringe order colored ring were photographed.Results: In 100 N, 90 degree angle loading in cervical and apical fringe order showed 2.50 and 1.39 in simple taper posts and 1.39 and 2.35 in DOUBLE taper post. In 150 N, 30 degree angle loading in cervical and apical fringe order showed 4 and 2.65 in simple taper posts, and 4 and 2.5 in DOUBLE taper post.Conclusion: In the vertical and oblique loads, DOUBLE taper fiber post showed better stress distribution than that of simple tapered posts.